ملخصات الابحاث

المجالات البحثية

قسم كمياء طبية

الابحاث العلمية

1 - Design and Synthesis of Novel Thienopyrimidine Derivatives with Potential Biological Activity (2024).

2 - Design, Synthesis and Evaluation of Novel Inhibitors of E2 Ubiquitin Conjugating Enzyme as Potential Breast Cancer Therapeutics (2024).

3 - Synthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazepine Derivatives for Biological Study " تشييد مشتقات جديدة من 1و3 بنزوديازين و1و3و4 بنزوتريازيبين وذلك للدراسة البيولوجية (2024).

4 - Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity (2023).

5 - Hybrid N-Acylcysteines as Dual-Acting Matrix Disruptive and Anti-Quorum Sensing Agents Fighting Pseudomonas aeruginosa Biofilms: Design, Synthesis, Molecular Docking Studies, and In Vitro Assays (2022).

6 - Synthesis and antimicrobial activity of newly synthesized 4-substituted-pyrazolo[3,4-d]pyrimidine derivatives (2017).

7 - Synthesis of 125I‐lamivudine and 125I‐lamivudine‐ursodeoxycholic acid codrug (2016).

8 - Synthesis and biological screening of new derivatives of 2,3-dihydro quinazolin-4(1H)-one and benzotriazepin- 5(2H)-one for central nervous system activity (2014).

9 - SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN- 4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS. (2013).

10 - Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides (2013).

11 - DESIGN AND SYNTHESIS AND IN VITRO ANTICANCER EVALUATION OF 4,6-DIAMINO 1,3,5-TRIAZINE-2-CARBOHYDRAZIDES AND CARBOXAMIDES (2013).

12 - SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN-4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS (2013).

13 - DESIGN AND SYNTHESIS OF N4, N9- DISUBSTITUTED SPERMINES FOR NON-VIRAL SIRNA DELIVERY – STRUCTURE – ACTIVITY RELATIONSHIP STUDIES OF SIFECTION EFFICIENCY VERSUS TOXICITY (2009).

14 - SYNTHESIS OF HEXAHYDRO-1H-PYRIDO (3, 2-C) AZEPINES AS HYPOTENSIVE AGENTS OF EXPECTED CALCIUM-CHANNEL BLOCKING ACTIVITY (2007).

15 - DESIGN, SYNTHESIS AND CYTOTOXIC ACTIVITY OF NOVEL AROYL-4-(2-CHLOROETHYL) SEMICARBAZID (2007).

16 - Increasing Sensitivity of Colorimetric Determination of Basic Drugs Through Ion pair Complex Formation (2005).

17 - SPECTROPHOTOMETRIC DETERMINATION OF HEPTAMOL AND MEXILETINE HYDROCHLORIDE VIA CHARGE TRANSFER OR ION PAIR FORMATION (2002).

18 - SYNTHESIS OF NEW N-ARYLMALEIMIDES AND ANALOGOUS AS POSSIBLE ANTIMICROBIAL AGENTS (2001).

19 - SYNTHESIS AND PRELIMINARY TESTING OF CERTAIN NEW TRIAZOLAQUINAZOLINE DERIVATIVES AS ANTINFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS (2000).

20 - UTILITY OF DICHLOROMALEIMIDE DERIVATIVE AS CHROMOGENIC REAGENT FOR THE SPECTROPHOTOMETRIC DETERMINATION OF CERTAIN FLUOROQUINOLOINES AND RELATED COMPOUNDS (1999).

21 - SYNTHESIS OF SOME NEW QUINOLINE DERIVATIVES OF POTENTIAL ANTIMICROBIAL ACTIVITY (1999).

22 - SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME NEW ARYLSULPHONYLUREA AND THIOUREA DERIVATIVES (1999).

23 - SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL HETEROCYCLIC DERIVATIVES OF FLURBIPROFEN (1998).

24 - REDUCTION OF 2, 3-DICHLOROMALEIC ANHYDRIDE III; ACYLATIVE REDUCTIVE ELIMINATION (1997).

25 - REACTION OF 2, 3- DICHLOROMALEIC ANHYDRIDE I: NITROSATIVE REDUCTIVE ELIMINATION; SYNTHESIS OF N-(2,6-DIMETHYLPHENYL)-2-(N-NITROSO-N-SUBSTITUTED)AMINO- SUCCINIMIDES (1996).

26 - REACTION OF 2, 3- DICHLORO MALEIC ANHYDRIDE*: III REACTION WITH BINUCLEOPHILIC ({4+2} CYCLOCONDENSATION) FOR SYNTHESIS OF COMPOUNDS WITH POTENTIAL ANTIMICROBIAL ACTIVITY (1994).

27 - SYNTHESIS OF SOME PYRIMIDO (1,6-A) INDOLE OF POTENTIAL PHARMACOLOGICAL INTEREST (1994).

28 - SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF CERTAIN QUINAZOLINE DERIVATIVES (1993).

29 - SYNTHESIS OF 3- SUBSTITUTED (6-BROMO-2-IMIDAZO {4, 5- B} PYRIDINYL) PROPIONIC ACID AS ANTIINFLAMMATORY, ANALGESIC, AND ANTIPYTRIC AGENTS (1993).

30 - SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIIFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS (1993).

31 - SPECTROPHOTOMETRIC DETERMINATION OF KETOPROFEN IN PHARMACEUTICAL PREPARATIONS BY MEANS OF CHARGE TRANSFER COMPLEXES (1993).

32 - SYNTHESIS OF SOME PYRIMIDO(4,,5,: 4,5) PYRIMIDO(1,6- A) INDOLE OF POTENTIAL ANTIINFLAMMATORY ANTIPYRETIC ACTIVITIES (1993).

33 - SYNTHESIS OF NEW CONDENSED PYRIMIDINES I (1992).

34 - DIFFENETIAL FIRST DERIVATIVE SPECTROPHOTOMETRIC DETERMINATION OF PROPRANOLOL (1992).

35 - APPLICATION OF REDUCTIVE NITROSATION IN SYNTHESIS OF PYROLOQUINOXALINES AS POTENTIAL ANTIMICROBIAL AGENTS (1992).

36 - N-2, 6-DIMETHYLPHENYL-2, 3-DICHLOROMALEIMIDE AS ANALYTICAL REAGENT FOR DETERMINATION OF ISONIAZIDE IN THE PRESENCE OF OTHER INGREDIENTS (1992).

37 - DIFFERENTIAL ZERO CROSSING FIRST DERIVATIVE PECTROPHOTOMETRY FOR THE DETERMINATION OF EPHEDRINE IN PURE AND DOSAGE FORM (1991).

38 - SYNTHESIS AND BIOLOGICAL ACTIVITY OF CERTAIN IBUPROFEN DERIVATIVES (1989).

39 - SYNTHESIS OF SOME S-TRIAZOLE DERIVATIVES FROM IBUPROFEN AS POTENTIAL ANTIINFLAMMATORY AGENTS (1989).

40 - Synthesis of certain Arylalkanoic Acid Derivatives of pharmacutical Interest (1900).

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